Extended spectrum β-lactamases (ESBLs) are enzymes produced by a variety of Gram negative bacteria which confer an increased resistance to commonly used antibiotics. They are a worrying global public health issue as infections caused by such enzyme-producing organisms are associated with a higher morbidity and mortality and greater fiscal burden. The ESBL profile detection can be perform the observation of a champagne-cork or a keyhole between a third or fourth generation cephalosporin and clavu

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