The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

Ming He, M.D., Ph.D., an assistant professor at the University of Alabama at Birmingham’s Marnix E. Heersink School of Medicine Department of Pathology Division of Molecular and Cellular Pathology, is ...

About half of Americans between 45 and 84 have atherosclerosis without knowing it. Diseases linked to atherosclerosis are the leading cause of death in the United States. The condition develops when ...

A research team led by Dr. Xiang David Li, Associate Professor from the Department of Chemistry, in collaboration with Dr. Karen Wing Yee Yuen from the School of Biological Sciences and Dr. Jason Wing ...

A new model for the nucleosome is presented. The histone octamer core is unchanged, but the location of the DNA is different. Since the highest number, and highest concentration of positively-charged ...

1 Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China 2 Department of Medicine, Rhode Island Hospital and Alpert Medical School, Brown University, ...

Rationale: The multifactorial nature of pulmonary hypertension (PH) suggests epigenetic changes as potential determinants of vascular remodeling through regulating gene expression (both up-regulated ...