President Masoud Pezeshkian’s rejection was Tehran’s first response to a letter the US president sent to the country’s supreme leader.

Ireland’s deputy premier is to appeal for “calm” and “measured” EU co-operation ahead of a major tariff announcement by US President Donald Trump expected on Wednesday. Tanaiste Simon Harris is due to ...

Melanie Roberts said she worried about internet and mobile bill increases, as she relied on these services to continue to work and speak to family.

A British explorer has become the first woman to solo traverse across Canada’s freezing Baffin Island a day earlier than expected. Camilla Hempleman-Adams battled temperatures as low as minus 40C and ...

The device, known as N-Tidal Diagnose, uses carbon dioxide sensors to measure changes in a patient’s lung function with results given in minutes.

The health department has announced that it has reached an agreement with Community Pharmacy England for a funding increase over two years.

Employers should give workers time off to attend potentially lifesaving cancer screening, the outgoing head of the NHS has said. Amanda Pritchard, who ends her tenure as NHS England chief executive on ...

Sir Keir Starmer and US President Donald Trump have agreed on the need to “keep up the collective pressure on Putin” during a phone call, Downing Street said.

Donald Trump has sent the King his “best wishes” in a phone call with Sir Keir Starmer, Downing Street has said. Opening the conversation on Sunday evening, which covered the war in Ukraine and a ...

NBC’s Kristen Welker asked Mr Trump if one potential route to a third term was having vice president JD Vance run for the top job and “then pass the baton to you”. “Well, that’s one,” the president ...

Chelsea’s lead at the Women’s Super League summit was cut to six points after West Ham ended the Blues’ season-long winning streak at Kingsmeadow in thrilling fashion. Sonia Bompastor’s side looked to ...

A fire at a historic former station house that killed three people, including a four-year-old girl, is not believed to have been caused by a criminal act, police have said, as a man who was arrested ...