Introduction Tocilizumab improves outcomes in critically ill patients with COVID-19. Whether other immune-modulator strategies are equally effective or better is unknown. Methods We investigated ...

Objectives Infliximab, an anti-TNF agent, is used to treat sarcoidosis that does not respond to corticosteroids or second-line agents. The efficacy of other anti-TNF agents, non-TNF biologics and ...

Introduction Combination of the noradrenergic atomoxetine with either the antimuscarinic aroxybutynin or trazodone has been shown to improve obstructive sleep apnoea (OSA) severity. However, ...

Severe community-acquired pneumonia (sCAP) is a major global health challenge, with high morbidity and mortality, especially among patients requiring intensive care. Despite advancements in ...

Background: There is little previous information of the effects of size fractioned particulate air pollution and source specific fine particles (PM 2.5; <2.5 μm) on asthma and chronic obstructive ...

4 Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, Australia Correspondence to: Dr D Breen, Intensive Care Unit, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW ...

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1 Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong 2 Department of Medicine and Therapeutics, Chinese University of Hong ...

Correspondence to Dr Audrey Winter, Department of Radiological Sciences, Medical Imaging Informatics, University of California, Los Angeles, CA 90095, USA; audrey.winter89{at}gmail.com Introduction We ...

Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators ...

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