The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

Facilities operated by the US Department of Energy (DOE) are required to have extensive worker safety and health programs by regulation. We describe how Argonne National Laboratory (ANL) has ...

Modulating the microenvironment of zeolite-encapsulated subnanometer metal active sites represents a frontier in the design of solid catalysts because of its marked impacts on the catalytic properties ...

The ortho-nitrobenzyl (ONB) group is one of the most widely utilized photocages for spatiotemporal control of biological processes via the light-triggered activation of small molecules and ...

In target-based drug discovery, quantification of target engagement is required to build structure–activity relationships and develop a potent clinical candidate. Target engagement data also provides ...

The development of single-atom catalysts (SACs) with site-specific and tunable catalytic functionalities remains a highly desirable yet challenging goal in catalysis. In this study, we report a SAC ...

Classical empirical force fields have dominated biomolecular simulations for over 50 years. Although widely used in drug discovery, crystal structure prediction, and biomolecular dynamics, they ...

Semiconductors form the foundational bedrock of modern electronics and numerous cutting-edge technologies. Particularly, semiconductors crafted from organic building blocks hold immense promise as ...

Extracellular vesicles (EVs) are a vital component in cell–cell communication and hold significant potential as biomarkers and therapeutic carriers. Having a reproducible and simple EV isolation ...

Fluorescence emitters with a multiple-resonant (MR) effect have become a research hotspot. These MR emitters mainly consist of polycyclic aromatic hydrocarbons with boron/nitrogen, nitrogen/carbonyl, ...

Near-infrared (NIR) polarization photodetectors based on 2D materials hold immense potential for numerous optoelectronic applications. To enhance the weak light-matter interaction in 2D materials, ...

A concise, scalable total synthesis of (−)-bipinnatin J is disclosed. Commencing from inexpensive starting materials, this marine diterpenoid was fashioned through a convergent synthesis enabled by Ni ...