Emergency hemopoiesis may maintain blood counts and a proinflammatory environment in MDS, AML, and ICUS. Altered neutrophil subset distributions in MDS and AML show diagnostic sensitivity, with ...

Neutropenia is the most common serious risk of cancer treatment. It occurs when white blood cells called neutrophils drop below a healthy range, putting you at increased risk of infections.

The effects of sargramostim and filgrastim on hematopoietic cells are described. Filgrastim is a lineage-specific colonystimulating factor (CSF), mainly affecting neutrophils. In addition to enhancing ...

The results of a study by researchers at Hokkaido University’s Faculty of Medicine have shown how composition of the gut microbiome is crucial to driving a process known as granulopoiesis that ...

In a recent Nature Reviews Immunology journal study, researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders. Study: Neutrophil ...

Neutrophils induce anti-inflammatory -- or M2 -- macrophages deep in their granulocyte core. The dense globular structures of granulomas in animals, particularly in the lungs, have been studied.

Neutrophils are the most abundant type of white blood cells, critical for immune defense and inflammation control. Traditionally, their role in cancer was seen as minor, but emerging evidence reveals ...

Two concepts are important to understanding how leukocytes become immunocompetent cells: proliferation and differentiation (Figure 6). Proliferation is the production of many cells from a single cell ...

Potential pro- and anti-tumor functions of tumor-associated neutrophils (TANs). TANs may either promote or inhibit tumorigenesis and tumor progression through various immune mechanisms. (Figure left) ...

Intestinal bacteria composition is crucial to driving the recovery of neutrophils counts in the blood of mice following treatments such as stem cell transplants or chemotherapy. White blood cells, or ...