The tetrahydrocannabinol (THC) content of cannabis has roughly quintupled in the past 2 decades, from around 4% in the 2000s to more than 20% in most legal dried cannabis in Canada by 2023.[1][1] The ...

Scope The Canadian Stroke Best Practice Recommendations are intended to provide up-to-date, evidence-based guidelines for the prevention and management of conditions that are of concern to the Heart ...

See related article at In this issue of CMAJ , Laura MacGregor describes her harrowing experience of seeking restitution following her son’s birth injury, which had left him with severe neurologic an ...

See related article at When I tell the story of my son’s birth, people are often surprised that I am not angry with the physician who wielded the forceps at his delivery, asphyxiating him and causing ...

An 86-year-old man presented to the emergency department with fever, headache, nuchal rigidity, and restricted neck rotation that developed 2 weeks after tooth extractions. He had received cefcapene ...

Obesity affects 8%–12% of pregnancies 1 A pre-pregnancy body mass index (BMI) of 30 kg/m 2 or greater is linked with an increased risk of adverse outcomes in pregnancy. 1 The risk of preeclampsia ...

Background: Ground-level falls are common among older adults and are the most frequent cause of traumatic intracranial bleeding. The aim of this study was to derive a clinical decision rule that ...

Recommendation The Canadian Task Force on Preventive Health Care recommends against instrument-based depression screening using a questionnaire with cut-off score to distinguish “screen positive” and ...

Background: The relation between emergency department opioid prescribing and subsequent harm is complex and poorly studied. We sought to quantify adverse outcomes, incremental risk, and rates of ...

Background: In Canada, low awareness of evidence-based interventions for the clinical management of alcohol use disorder exists among health care providers and people who could benefit from care. To ...

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department.[1][1] It is a clinical spectrum of ...

Diet is associated with depressive symptoms A 2024 umbrella review — including nearly 10 million participants enrolled in observational studies — found that people who consumed more ultra-processed ...