Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...

Two-component signal transduction systems (TCS) are fundamental to the ability of bacteria and certain lower eukaryotes to sense and respond to environmental changes. Typically composed of a sensor ...

Researchers at the Department of Pharmacology and Toxicology at the University Medical Center Göttingen (UMG) have discovered a key genetic regulatory mechanism that becomes disrupted in heart failure ...