The Arizona Cardinals lost on Sunday in embarrassing fashion, a 45-17 drubbing from the Los Angeles Rams in front of the home fans at State Farm Stadium. They started playing well on offense, scoring 10 points in their first three drives, but then things fell apart as they didn't score again until it was 45-10.

The Rams scored three rushing and three passing TDs for the first time since 2001, when Kurt Warner and company ran roughshod over defenses.

The Rams amassed 530 yards of total offense in the 45-17 win, their most in a game since the 2019 season, and ran for 249 yards, their best total since a divisional round playoff game following

Matthew Stafford threw for 281 yards and three touchdowns, Puka Nacua and Blake Corum both scored twice and the Los Angeles Rams rolled past the Arizona Cardinals 45-17

WOODLAND HILLS, Ca. On Sunday, Los Angeles Rams wide receiver Puka Nacua was brilliant, hauling in seven catches for 167 yards and two touchdowns. Nacua's big day would be a massive factor in the Rams' blowout win over the Arizona Cardinals and his time in the end zone gave the superstar a career first.

Rams vs. Cardinals will broadcast nationally on FOX in Week 14 of the 2025 NFL season. Kenny Albert and Jonathan Vilma will call the game from the booth at State Farm Stadium, Streaming options for the game include FuboTV, which offers a free trial to new subscribers.

Jonathan Gannon admits the Cardinals were outplayed in every phase during a “humbling” loss to the Rams, their second five-game skid of 2025.

Cardinals quarterback Jacoby Brissett passed for 271 yards, two touchdowns and an interception, and Michael Wilson had 11 catches for 142 yards and two scores, but that was about it on offense, as they rushed for only 51 yards as a team and had 314 total yards. The offense scored 17 points for the third consecutive game.