Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme ...
Endoplasmic reticulum–associated degradation (ERAD) is a cellular protein quality-control process that disposes of proteasomal substrates from the early secretory pathway. Recent work shows that the ...
Cell membranes are both controlled borders with the outside world as well as dynamic platforms for organizing cell signalling, metabolic pathways, and ultrastructure assembly. All of these key events ...
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