Physical activity stimulates the release of endorphins (natural painkillers) and promotes the production of anti-inflammatory ...

Nearly everyone is familiar with the feeling of accidentally touching a hot vessel or holding onto something freezing for too long. Normally, pain serves to protect from potential harm, but when the ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

UNC School of Medicine research reveals a pain control pathway from the cortex to cerebellum crucial for placebo analgesia – when the expectation of pain relief leads to pain alleviation without a ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Men and women experience pain differently, and until now, scientists didn’t know why. New research says it may be in part due to differences in male and female nerve cells. Pain-sensing nerve cells ...

Researchers have investigated the role that estrogen plays in signaling more gut pain, and it isn't working alone.

A variety of pain-relieving drugs are available both over the counter and by prescription. SelectStock/Vetta via Getty Images Without the ability to feel pain, life is more dangerous. To avoid injury, ...

The American College of Cardiology (ACC) expert decision pathway for chest pain can safely and effectively rule out acute coronary syndromes in most patients, but not for those with known coronary ...