Patent foramen ovale (PFO) is the most common congenital heart abnormality of fetal origin and is present in approximately ∼25% of the worldwide adult population. PFO is the consequence of failed ...

Whether closure of a patent foramen ovale reduces the risk of recurrence of ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown. In a multicenter, randomized, open-label ...

The efficacy of closure of a patent foramen ovale (PFO) in the prevention of recurrent stroke after cryptogenic stroke is uncertain. We investigated the effect of PFO closure combined with ...

Patent foramen ovale (PFO) has been linked to ischemic strokes of undetermined cause (cryptogenic strokes). PFO—a remnant of fetal circulation when the foramen ovale does not seal after birth—can ...

Patent foramen ovale (PFO) may be associated with migraine, especially migraine with aura (MA), when the PFO is permanent right-left shunt (RLS), large RLS, and large-size PFO, a recent study found.

Please provide your email address to receive an email when new articles are posted on . High-risk patent foramen ovale was independently linked to a higher risk for decompression illness in scuba ...

A “dose-response” relationship may exist between migraine and patent foramen ovale (PFO), according to a review published in Frontiers in Neurology. According to the American Heart Association, a PFO ...

Because the benefits of patent foramen ovale closure were once in question, physicians remain hesitant about its use in clinical practice. Recent data, however, have confirmed the safety and efficacy ...

In the womb, fetuses have an opening in the upper chambers of the heart known as a foramen ovale. While the opening is supposed to close naturally after birth, for many it never does. That's when it's ...