Notch signalling is a conserved cell‐to‐cell communication pathway that directs the fate of multipotent precursors and stem cells. Engagement of Notch receptors by membrane-bound ligands triggers ...
Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...
Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...
Development of the mature mammary gland requires numerous signaling pathways engaged by secreted factors and cell:cell interactions. My overall interest is in studying the signaling pathways that ...