A 41-year-old male with IgG kappa multiple myeloma is described. He developed a free gamma heavy chain without an accompanying light chain following high-dose chemotherapy and autologous peripheral ...
Abbreviations: EFS, event-free survival; OS, overall survival; HR, hazard ratio; NCCTG, North Central Cancer Treatment Group; IPI, International Prognostic Index; MER ...
In a second study that included both solid organ and allogeneic hematopoietic stem cell (HSC) recipients, 6 we demonstrated that some PTLD cases manifested a monoclonal FLC pattern, that is, a ...
Background: Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in ...
MM often goes undetected until its later stages because it presents with non-specific symptoms, including fatigue, weight loss, bone pain, and recurrent infections. 2,3 However, better awareness, ...
Elevated Serum Free Light Chains Are Associated With Event-Free and Overall Survival in Two Independent Cohorts of Patients With Diffuse Large B-Cell Lymphoma Forty-three percent of patients achieved ...
Therapy-related B-lymphoblastic leukemia (B-ALL) following treatment for multiple myeloma is a rare occurrence. Despite its rarity and the lack of recognition by the World Health Organization as a ...