Nature

Multi-modal deep learning enables efficient and accurate annotation of enzymatic active sites

Annotating active sites in enzymes is crucial for advancing multiple fields including drug discovery, disease research, enzyme engineering, and synthetic biology. Despite the development of numerous ...
Labroots

A New Way to Describe Enzyme Kinetics

The Michaelis-Menten equation is used to describe the dynamics of an enzymatic reaction, in which an enzyme interacts with a substrate to generate some product before the enzyme is released. Cells are ...
Phys.org

Enzymes are the engines of life—machine learning could help scientists design new ones

Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the attention of scientists like me. Consider muscle movement. Your body ...
Nature

Deep graph level anomaly detection with contrastive learning

Graph level anomaly detection (GLAD) aims to spot anomalous graphs that structure pattern and feature information are different from most normal graphs in a graph set, which is rarely studied by other ...