Delivering therapies to the brain remains a major challenge due to the limited permeability of the blood-brain barrier. In a ...

In a study published in the Journal of Extracellular Vesicles, scientists from the UF Health Cancer Institute have found a way to make treatment for a notoriously aggressive breast cancer more ...

Development of effective medications for central nervous system (CNS) disorders has long been plagued by a high failure rate in clinical trials. One ...

Its proprietary and differentiated lipid nanoparticle (LNP) platform is a cornerstone in advancing next-generation messenger ...

As part of the first-in-human trial, participants received more than 15 times the standard dose of the chemotherapy drug doxorubicin every 21 days for up to one year. “Usually, a patient can only ...

Abundant and persistent, red blood cells have a lifetime of about four months in the human body and travel to every organ and tissue. They could soon be leveraged to transport more than oxygen and ...

"The blood-brain barrier prevents most drug uptake into the brain," Dr. Padmanabhan said. "Insights from this device will help inform ultrasound treatment protocols and establish a balance where ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...

Glaucoma has long been treated as a plumbing problem of the eye, managed mainly by lowering pressure rather than protecting ...

A new device combining ultrasound and advanced imaging to provide crucial information for the safe delivery of drugs into the brain has been developed by University of Queensland researchers. Dr.

The mini review brings together emerging evidence showing that glial cells actively influence disease progression and ...