Researchers identify the hippocampus and microglia as the "tipping point" that determines if chronic pain leads to depression ...

For over a decade, neuroscientists have been trying to figure out how neurogenesis (the birth of new neurons) and neuroplasticity (the malleability of neural circuits) work together to reshape how we ...

The dentate gyrus is one of only two areas in the brain where new neurons are formed continuously in adults through a process called neurogenesis. When a new granule cell neuron is formed in the ...

The dentate gyrus (DG) is the input region of the hippocampus and plays an important role in learning and memory. Although emerging evidence suggests that abnormal expression of the polycomb ...

In a study published in Nature Communications, scientists determine that schizophrenia-associated mutations in synapse-associated protein 97 (SAP97) cause an extreme increase in glutamatergic ...

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis—the birth of new neurons—is now a widely ...

Damage to a part of the brain that regulates hyperactivity can contribute to both memory problems and seizures in the most common form of epilepsy, according to research at the University of Wisconsin ...