One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...
A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...
Neil Hunter, a professor in the Department of Microbiology and Molecular Genetics, has discovered a crucial step in how chromosomes stay connected during the development for egg cells and sperm, ...
Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...
One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we've worked ...
In a breakthrough that could boost de-extinction efforts, scientists have determined the 3D structure of a woolly mammoth's genome from a 52,000-year-old piece of freeze-dried skin. When you purchase ...
The centromere is necessary for the transport of chromosomes during cell division and, therefore, for the correct ...