A methylation mark on translation factor eEF1A selectively speeds decoding of rare, wobble-weak codons, boosting KRAS ...

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this ...

KRAS cancer treatment may have a new upstream target: the METTL13 enzyme that helps tumors overproduce KRAS protein and ...

St. Jude scientists showed that METTL13-driven methylation of the translation factor eEF1A selectively speeds decoding of ...

For decades, scientists working with genetic material have labored with a few basic rules in mind. To start, DNA is transcribed into messenger RNA (mRNA), and mRNA is translated into proteins, which ...

Our genes are written in long strings of three-letter units composed of four different nucleotides. These units - or codons - specify one of many amino acids, the building blocks of proteins. Multiple ...

One of modern biologists' most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms. Part of the motivation for ...

Superimposed on the genetic sequences coding for amino acids is a second genetic code. This second genetic code, which makes use of dual-use codons, or duons, specifies how genes are controlled. The ...

The genetic code is made up of a total of 64 base triplets or codons. At least one codon encodes the information for each of the 20 amino acids used in the synthesis of proteins during translation.

A microscopic organism from a freshwater pond is playing by a different set of genetic rules. The newly identified protist, Oligohymenophorea sp. PL0344, which scientists stumbled across while ...

A central tenet of biology may need updating given new measurements of start codons. For decades, scientists working with genetic material have labored with a few basic rules in mind. To start, DNA is ...

Cells working with an expanded genetic code could make more diverse medicines. A new study shows scientists are within striking distance. One of modern biologists' most ambitious goals is to learn how ...