If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Entropic forces have been argued to drive bacterial chromosome segregation during replication. In many bacterial species, however, specifically evolved mechanisms, such as loop-extruding SMC complexes ...

Scientists assess bacterial growth trajectories to better predict infectious capacity and the conditions that aid proliferation. This article explores the key factors that influence bacterial ...

Intracellular DNA can become damaged and/or distorted through a multitude of endogenous and exogenous sources (e.g., post-replication mismatches, base oxidation, cyclobutane pyrimidine dimers) 1,2.

Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the presence of fluoroquinolones. Blue color arrow indicates downregulation, while ...

Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...