Amide bonds are ubiquitous in pharmaceuticals, agrochemicals and biomolecules, and their formation underpins the synthesis of peptides, proteins and small-molecule therapeutics. Traditional chemical ...

Amide bonds are among the most ubiquitous linkages in natural products, pharmaceuticals and advanced materials. Traditional approaches rely on stoichiometric coupling reagents to activate carboxylic ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

“Amide’s significant advances in peptide synthesis has allowed us to obtain synthetic versions of very long peptides which historically would have been intractable,” said Mack Flinspach, Executive ...

Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...

(4) Carboxylic acids and amines themselves do not react to form amides. Instead, a process activates the carboxylic acid, making it susceptible to amide formation. I don't get paid enough to broach ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...

A study published in Small examined how modifying the surface charge of covalent organic frameworks (COFs) affects platinum (Pt) photodeposition and photocatalytic hydrogen evolution. The researchers ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a biotech that synthesizes challenging peptides, announced today that it has begun commercializing its novel peptide manufacturing platform. The ...