A-kinase anchoring proteins (AKAPs) target protein kinase A (PKA) to distinct subcellular locations. This positions the enzyme at regions of cyclic-AMP production and confines phosphorylation to a ...
Specificity in cell signalling can be influenced by the targeting of different enzyme combinations to substrates. The A-kinase anchoring protein AKAP79/150 is a multivalent scaffolding protein that ...