In a recent study posted to the bioRxiv* preprint server, researchers discovered compounds able to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain 1 (Mac1) and ...

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

Purines are heterocyclic aromatic molecules that are among the oldest and most influential biochemical compounds in evolutionary history. 1 The purine nucleotide adenosine triphosphate (ATP) is the ...

ATP-ADP exchange was estimated in the presence of plasma membrane H+-ATPase of oat (Avena sativa) roots partially purified with Triton X-100 by measuring [14C]ATP formation from [14C]ADP. Most studies ...

Arabidopsis (Arabidopsis thaliana) possesses two isoforms of plastidic ATP/ADP transporters (AtNTT1 and AtNTT2) exhibiting similar biochemical properties. To analyze the function of both isoforms on ...

In a recent study published in the journal Nature Communications, researchers structurally analyzed adenine nucleotide control and neurodegenerative diseases in ClC-3 exchangers. Study: Structural ...

Adenosine 5′-triphosphate, abbreviated ATP and usually expressed without the 5′-, is an important “energy molecule” found in all life forms. Specifically, it is a coenzyme that works with enzymes such ...

TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity against drug-sensitive and drug-resistant TB. TMC207 inhibits the proton pump of mycobacterial ...

ATP (adenosine triphosphate) is the energy-carrying molecule used in cells because it can release energy very quickly. Energy is released from ATP when the end phosphate is removed. Once ATP has ...