In Sporting News' picks and predictions for Week 13, the red-hot Texans deal the Colts another loss in a key AFC South showdown while the Shedeur Sanders show in Cleveland screeches to a halt.

The Houston Texans' league-best defense will have a tough task on their hands rolling into their Week 13 matchup against their division rival Indianapolis Colts and their machine of an offense that's led them near the top of the AFC through the first half of this NFL season.

Daniel Jones -- coming off a multi-touchdown passing game -- and the Indianapolis Colts meet the Houston Texans in Week 13, on Sunday at 1 p.m. ET. To be specific, he passed for 181 yards and two TDs. Game Time: 1 p.m.

A surging Texans team, bolstered by Stroud's return and a dominant defense, eyes a crucial road win to seize control of their playoff destiny.

The Houston Texans will have a crucial matchup at the Indianapolis Colts on Sunday that could factor into their postseason hopes.

The Texans beat Buffalo despite a poor second half offensively. That will have to change Sunday against the AFC-South leading Colts.

The Houston Texans went 0-2 with Sunday’s 31-20 loss to the Indianapolis Colts at NRG Stadium. QB C.J. Stroud threw for 384 yards and completed 30/47 throws with two touchdowns but it wasn’t enough for a win. The Colts got their first win while the ...

All of a sudden, the race for the AFC South division title has tightened up. The Indianapolis Colts have been in control of the division race all season long, and they do still have the lead. However, Jacksonville and Houston are lurking close by.

Oct 13, 2024; Foxborough, Massachusetts, USA; Houston Texans running back Dameon Pierce (31) reacts after scoring a touchdown against the New England Patriots during the second half at Gillette Stadium. Mandatory Credit: Brian Fluharty-Imagn Images | Brian Fluharty-Imagn Images